Posted on November 10, 2021November 10, 2021N4BP1 utilises a novel mechanism for interaction with linear ubiquitin. Our work about N4BP1 and M1-linked ubiquitin is now on bioRxiv: N4BP1 is dimerization-dependent linear ubiquitin reader regulating TNFR1 signalling through linear ubiquitin binding and Caspase-8-mediated processing.